Suspect histoplasmosis in returning travellers from an endemic area presenting with fever and cough

Histoplasmosis can present in a variety of ways, making it difficult to diagnose. Dr Staffolani and colleagues carried out a systematic review of 835 cases of histoplasmosis (including 45 clusters) from the literature, among immunocompetent patients who had recently returned from an endemic area. Manifestations included fever (91%), cough (55%), constitutional symptoms (58%), headache (52%) and chest pain (41%).

Cluster of paracoccidioidomycosis cases in children in Argentina during the 1982-3 El Niño anomaly

Serious systemic paracoccidioidomycosis infections are often associated with men working in agriculture. Dr Guisano and colleagues describe a cluster of six cases in children in the NEA area of Argentina that occurred during the 1982-3 El Niño Southern Oscillation climatic anomaly, and suggest that climatic and anthropogenic changes may have played a role

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